4DAN

Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-fluoroadenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Purine nucleoside phosphorylase deoD-type	polymer	253	27562.1	2	UniProt (O34925) Pfam (PF01048)	Bacillus subtilis	PNP, Purine nucleoside phosphorylase II, PU-NPase II
2	C, D (A, B)	2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL	non-polymer		285.2	2	Chemie (2FA)

Sequence modifications

A, B: 1 - 233 (UniProt: O34925)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Asp 225	Glu 225	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55124.3
Non-Polymers*	Number of molecules	2
	Total formula weight	570.5
All*	Total formula weight	55694.7

*Water molecules are not included.