4DAJ
Structure of the M3 Muscarinic Acetylcholine Receptor
Summary for 4DAJ
Entry DOI | 10.2210/pdb4daj/pdb |
Descriptor | Muscarinic acetylcholine receptor M3, Lysozyme, (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, PHOSPHATE ION (3 entities in total) |
Functional Keywords | g protein-coupled receptor, muscarinic receptor, acetylcholine receptor, signaling protein, hydrolase |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P08483 |
Total number of polymer chains | 4 |
Total formula weight | 222480.95 |
Authors | Kruse, A.C.,Hu, J.,Pan, A.C.,Arlow, D.H.,Rosenbaum, D.M.,Rosemond, E.,Green, H.F.,Liu, T.,Chae, P.S.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Wess, J.,Kobilka, B. (deposition date: 2012-01-12, release date: 2012-02-22, Last modification date: 2023-09-13) |
Primary citation | Kruse, A.C.,Hu, J.,Pan, A.C.,Arlow, D.H.,Rosenbaum, D.M.,Rosemond, E.,Green, H.F.,Liu, T.,Chae, P.S.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Wess, J.,Kobilka, B.K. Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature, 482:552-556, 2012 Cited by PubMed: 22358844DOI: 10.1038/nature10867 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
Download full validation report