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4DA4

Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA

Summary for 4DA4
Entry DOI10.2210/pdb4da4/pdb
DescriptorDNA (cytosine-5)-methyltransferase 1, DNA_UPPER_STRAND, DNA_LOWER_STRAND, ... (7 entities in total)
Functional Keywordsmaintenance dna methylation, covalent complex, transferase-dna complex, transferase/dna
Biological sourceMus musculus (mouse)
More
Cellular locationNucleus: P13864
Total number of polymer chains6
Total formula weight213997.43
Authors
Song, J.,Patel, D.J. (deposition date: 2012-01-12, release date: 2012-02-22, Last modification date: 2024-02-28)
Primary citationSong, J.,Teplova, M.,Ishibe-Murakami, S.,Patel, D.J.
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation.
Science, 335:709-712, 2012
Cited by
PubMed: 22323818
DOI: 10.1126/science.1214453
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

数据于2024-03-27公开中

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