4DA4

Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA

4DA4 の概要

分子名称DNA (cytosine-5)-methyltransferase 1, DNA_UPPER_STRAND, DNA_LOWER_STRAND, ... (7 entities in total)
機能のキーワードmaintenance dna methylation, covalent complex, transferase-dna complex, transferase/dna
由来する生物種Mus musculus (mouse)
詳細
細胞内の位置Nucleus P13864
ポリマー鎖数6
分子量合計213997.43
構造登録者
Song, J.,Patel, D.J. (登録日: 2012-01-12, 公開日: 2012-02-22)
主引用文献
Song, J.,Teplova, M.,Ishibe-Murakami, S.,Patel, D.J.
Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation.
Science, 335:709-712, 2012
PubMed: 22323818 (主引用文献が同じPDBエントリー)
DOI: 10.1126/science.1214453
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.6 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.235170.1%7.2%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード