4D9M

Crystal structure of Diaminopropionate ammonia lyase from Escherichia coli in complex with aminoacrylate-PLP azomethine reaction intermediate

Summary for 4D9M

Entry DOI	10.2210/pdb4d9m/pdb
Related	4D9G 4D9I 4D9K 4D9N
Descriptor	Diaminopropionate ammonia-lyase, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid (3 entities in total)
Functional Keywords	fold type ii plp-dependent enzyme, tryptophan synthase beta subunit-like plp-dependent enzymes superfamily, lyase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	87377.24
Authors	Bisht, S.,Rajaram, V.,Bharath, S.R.,Murthy, M.R.N. (deposition date: 2012-01-11, release date: 2012-04-25, Last modification date: 2023-11-08)
Primary citation	Bisht, S.,Rajaram, V.,Bharath, S.R.,Kalyani, J.N.,Khan, F.,Rao, A.N.,Savithri, H.S.,Murthy, M.R.N. Crystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and Catalysis J.Biol.Chem., 287:20369-20381, 2012 Cited by PubMed: 22505717 DOI: 10.1074/jbc.M112.351809 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation