4D7K

Crystal structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) from Streptomyces davawensis

Summary for 4D7K

Entry DOI	10.2210/pdb4d7k/pdb
Descriptor	SAM-DEPENDENT METHYLTRANSFERASES (2 entities in total)
Functional Keywords	transferase, methyltransferase, flavin, riboflavin, roseoflavin biosynthesis, alpha/beta twisted open-sheet
Biological source	STREPTOMYCES DAVAWENSIS JCM 4913
Total number of polymer chains	6
Total formula weight	232852.87
Authors	Uhl, M.K.,Gruber, K. (deposition date: 2014-11-25, release date: 2016-01-13, Last modification date: 2024-05-01)
Primary citation	Tongsook, C.,Uhl, M.K.,Jankowitsch, F.,Mack, M.,Gruber, K.,Macheroux, P. Structural and Kinetic Studies on Rosa, the Enzyme Catalysing the Methylation of 8-Demethyl-8-Amino-D-Riboflavin to the Antibiotic Roseoflavin FEBS J., 283:1531-, 2016 Cited by PubMed: 26913589 DOI: 10.1111/FEBS.13690 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation