4D6T

Cytochrome bc1 bound to the 4(1H)-pyridone GW844520

4D6T の概要

• エントリーDOI: 10.2210/pdb4d6t/pdb
• 関連するPDBエントリー: 4D6U
• 分子名称: CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL, CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL, ... (19 entities in total)
• 機能のキーワード: electron transport, cytochrome bc1, pyridone, membrane protein, complex
• 由来する生物種: BOS TAURUS (CATTLE); 詳細
• 細胞内の位置: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P31800 P23004 P23004; Mitochondrion inner membrane; Single-pass membrane protein: P13272 P13272; Mitochondrion inner membrane ; Multi-pass membrane protein : P00157; Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side: P00125; Mitochondrion inner membrane: P00129 P13271 P00126 P00130
• タンパク質・核酸の鎖数: 20
• 化学式量合計: 561767.54

構造登録者

Capper, M.J.,O'Neill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V. (登録日: 2014-11-14, 公開日: 2015-01-14, 最終更新日: 2023-12-20)

• 主引用文献: Capper, M.J.,O'Neill, P.M.,Fisher, N.,Strange, R.W.,Moss, D.,Ward, S.A.,Berry, N.G.,Lawrenson, A.S.,Hasnain, S.S.,Biagini, G.A.,Antonyuk, S.V.; Antimalarial 4(1H)-Pyridones Bind to the Qi Site of Cytochrome Bc1.; Proc.Natl.Acad.Sci.USA, 112:755-, 2015; PubMed: 25564664; DOI: 10.1073/PNAS.1416611112

実験手法

X-RAY DIFFRACTION (3.57 Å)