4D5Y

Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state

This is a large structure.

Summary for 4D5Y

Related4D5L 4D5N 4D61 4D67
EMDB information2810
Descriptor60S RIBOSOMAL PROTEIN UL2, 60S RIBOSOMAL PROTEIN UL3, 60S RIBOSOMAL PROTEIN UL4, ... (46 entities in total)
Functional Keywordscrpv ires, ribosome, termination, release factors
Biological sourceORYCTOLAGUS CUNICULUS (RABBIT)
Total number of polymer chains46
Total molecular weight2578728.21
Authors
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T. (deposition date: 2014-11-07, release date: 2015-03-04, Last modification date: 2017-08-23)
Primary citation
Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T.
Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57:422-, 2015
PubMed: 25601755 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2014.12.016
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone462.7%4.2%0.21MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures