4D1X

CDK2 in complex with Luciferin

Summary for 4D1X

• Entry DOI: 10.2210/pdb4d1x/pdb
• Related: 4D1Z
• Descriptor: CYCLIN-DEPENDENT KINASE 2, (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid (3 entities in total)
• Functional Keywords: transferase, kinase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941
• Total number of polymer chains: 1
• Total formula weight: 34256.81

Authors

Rothweiler, U.,Engh, R.A. (deposition date: 2014-05-05, release date: 2015-03-18, Last modification date: 2023-12-20)

• Primary citation: Rothweiler, U.,Eriksson, J.,Stensen, W.,Leeson, F.,Engh, R.A.,Svendsen, J.S.; Luciferin and Derivatives as a Dyrk Selective Scaffold for the Design of Protein Kinase Inhibitors.; Eur.J.Med.Chem., 94:140-, 2015; PubMed: 25768698; DOI: 10.1016/J.EJMECH.2015.02.035

Experimental method

X-RAY DIFFRACTION (2.1 Å)