4CYY

The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation

Summary for 4CYY

Entry DOI	10.2210/pdb4cyy/pdb
Related	4CYF 4CYG 4CYU
Descriptor	PANTETHEINASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	hydrolase, inflammation, oxidative stress, metabolic disease, coa biosynthesis
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	57634.45
Authors	Boersma, Y.L.,Newman, J.,Adams, T.E.,Sparrow, L.,Cowieson, N.,Lucent, D.,Krippner, G.,Bozaoglu, K.,Peat, T.S. (deposition date: 2014-04-16, release date: 2014-12-10, Last modification date: 2023-12-20)
Primary citation	Boersma, Y.L.,Newman, J.,Adams, T.E.,Cowieson, N.,Krippner, G.,Bozaoglu, K.,Peat, T.S. The Structure of Vanin-1: A Key Enzyme Linking Metabolic Disease and Inflammation Acta Crystallogr.,Sect.D, 70:3320-, 2014 Cited by PubMed: 25478849 DOI: 10.1107/S1399004714022767 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.89 Å)

Structure validation