4CY2
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
Summary for 4CY2
Entry DOI | 10.2210/pdb4cy2/pdb |
Related | 4CY1 4CY3 4CY5 |
Descriptor | WD REPEAT-CONTAINING PROTEIN 5, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, ... (4 entities in total) |
Functional Keywords | transcription, epigenetic regulator, histone acetylation, chromatin |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P61964 Q9H9L4 Q7Z3B3 |
Total number of polymer chains | 3 |
Total formula weight | 37661.55 |
Authors | Dias, J.,Brettschneider, J.,Cusack, S.,Kadlec, J. (deposition date: 2014-04-09, release date: 2014-05-14, Last modification date: 2023-12-20) |
Primary citation | Dias, J.,Van Nguyen, N.,Georgiev, P.,Gaub, A.,Brettschneider, J.,Cusack, S.,Kadlec, J.,Akhtar, A. Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28:929-, 2014 Cited by PubMed: 24788516DOI: 10.1101/GAD.240200.114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report