4CXN
Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form I
Summary for 4CXN
Entry DOI | 10.2210/pdb4cxn/pdb |
Related | 4CXL |
Descriptor | INSULIN A CHAIN, INSULIN B CHAIN (3 entities in total) |
Functional Keywords | hormone, diabetes |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5845.70 |
Authors | Kosinova, L.,Veverka, V.,Novotna, P.,Collinsova, M.,Urbanova, M.,Jiracek, J.,Moody, N.R.,Turkenburg, J.P.,Brzozowski, A.M.,Zakova, L. (deposition date: 2014-04-07, release date: 2014-05-28, Last modification date: 2023-12-20) |
Primary citation | Kosinova, L.,Veverka, V.,Novotna, P.,Collinsova, M.,Urbanova, M.,Moody, N.R.,Turkenburg, J.P.,Jiracek, J.,Brzozowski, A.M.,Zakova, L. An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53:3392-, 2014 Cited by PubMed: 24819248DOI: 10.1021/BI500073Z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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