4CVH

Crystal structure of human isoprenoid synthase domain-containing protein

Summary for 4CVH

Entry DOI	10.2210/pdb4cvh/pdb
Descriptor	ISOPRENOID SYNTHASE DOMAIN-CONTAINING PROTEIN, MAGNESIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm, cytosol : A4D126
Total number of polymer chains	1
Total formula weight	46227.19
Authors	Kopec, J.,Froese, D.S.,Krojer, T.,Newman, J.,Kiyani, W.,Goubin, S.,Strain-Damerell, C.,Vollmar, M.,von Delft, F.,Burgess-Brown, N.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Lefeber, D.J.,Yue, W.W. (deposition date: 2014-03-27, release date: 2015-02-04, Last modification date: 2018-01-24)
Primary citation	Riemersma, M.,Froese, D.S.,Van Tol, W.,Engelke, U.F.,Kopec, J.,Van Scherpenzeel, M.,Ashikov, A.,Krojer, T.,von Delft, F.,Tessari, M.,Buczkowska, A.,Swiezewska, E.,Jae, L.T.,Brummelkamp, T.R.,Manya, H.,Endo, T.,Van Bokhoven, H.,Yue, W.W.,Lefeber, D.J. Human Ispd is a Cytidyltransferase Required for Dystroglycan O-Mannosylation. Chem.Biol., 22:1643-, 2015 Cited by PubMed: 26687144 DOI: 10.1016/J.CHEMBIOL.2015.10.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation