4CQG
The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK selective inhibitor
Summary for 4CQG
Entry DOI | 10.2210/pdb4cqg/pdb |
Descriptor | Maternal embryonic leucine zipper kinase, 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 38909.86 |
Authors | Cho, Y.S.,Kang, Y.J.,Cho, H.S. (deposition date: 2014-02-17, release date: 2014-07-09, Last modification date: 2023-12-20) |
Primary citation | Cho, Y.S.,Kang, Y.,Kim, K.,Cha, Y.J.,Cho, H.S. The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor. Biochem.Biophys.Res.Commun., 447:7-11, 2014 Cited by PubMed: 24657156DOI: 10.1016/j.bbrc.2014.03.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.57 Å) |
Structure validation
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