4CQG

The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK selective inhibitor

Summary for 4CQG

Entry DOI	10.2210/pdb4cqg/pdb
Descriptor	Maternal embryonic leucine zipper kinase, 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone, SULFATE ION, ... (4 entities in total)
Functional Keywords	transferase
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	38909.86
Authors	Cho, Y.S.,Kang, Y.J.,Cho, H.S. (deposition date: 2014-02-17, release date: 2014-07-09, Last modification date: 2023-12-20)
Primary citation	Cho, Y.S.,Kang, Y.,Kim, K.,Cha, Y.J.,Cho, H.S. The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor. Biochem.Biophys.Res.Commun., 447:7-11, 2014 Cited by PubMed: 24657156 DOI: 10.1016/j.bbrc.2014.03.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.57 Å)

Structure validation