4CP3
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
Summary for 4CP3
Entry DOI | 10.2210/pdb4cp3/pdb |
Descriptor | B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN (3 entities in total) |
Functional Keywords | immune system, btb/poz, transcriptional repressor, rifamycin, antibiotic, smrt, inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: P41182 |
Total number of polymer chains | 2 |
Total formula weight | 29304.09 |
Authors | Evans, S.E.,Fairall, L.,Goult, B.T.,Jamieson, A.G.,Ferrigno, P.K.,Ford, R.,Wagner, S.D.,Schwabe, J.W.R. (deposition date: 2014-01-31, release date: 2014-03-19, Last modification date: 2023-12-20) |
Primary citation | Evans, S.E.,Goult, B.T.,Fairall, L.,Jamieson, A.G.,Ko Ferrigno, P.,Ford, R.,Schwabe, J.W.R.,Wagner, S.D. The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain. Plos One, 9:90889-, 2014 Cited by PubMed: 24595451DOI: 10.1371/JOURNAL.PONE.0090889 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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