4CP3
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | B-CELL LYMPHOMA 6 PROTEIN | polymer | 124 | 14228.5 | 2 | UniProt (P41182) Pfam (PF00651) | HOMO SAPIENS (HUMAN) | BCL-6, B-CELL LYMPHOMA 5 PROTEIN, BCL-5, PROTEIN LAZ-3, ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 27, ZINC FINGER PROTEIN 51 |
| 2 | C (B) | RIFABUTIN | non-polymer | 847.0 | 1 | Chemie (RBT) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 128 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | expression tag |
| Ala 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Gln 8 | - | expression tag |
| Arg 67 | Cys 67 | engineered mutation |
| Asn 84 | Cys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28457.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 847.0 | |
| All* | Total formula weight | 29304.1 |
