4CNO

Structure of the Salmonella typhi Type I dehydroquinase inhibited by a 3-dehydroquinic acid derivative

Summary for 4CNO

Entry DOI	10.2210/pdb4cno/pdb
Related	4CNN 4CNP
Descriptor	3-DEHYDROQUINATE DEHYDRATASE, (2R)-2-METHYL-3-DEHYDROQUINIC ACID (3 entities in total)
Functional Keywords	lyase, inhibitor, protein binding, shikimis acid pathway, substrate specificity
Biological source	SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI
Total number of polymer chains	4
Total formula weight	111540.68
Authors	Otero, J.M.,Llamas-Saiz, A.L.,Maneiro, M.,Peon, A.,Lence, E.,Lamb, H.,Hawkins, A.R.,Gonzalez-Bello, C.,van Raaij, M.J. (deposition date: 2014-01-23, release date: 2014-10-08, Last modification date: 2023-12-20)
Primary citation	Maneiro, M.,Peon, A.,Lence, E.,Otero, J.M.,Van Raaij, M.J.,Thompson, P.,Hawkins, A.R.,Gonzalez-Bello, C. Insights into substrate binding and catalysis in bacterial type I dehydroquinase. Biochem. J., 462:415-424, 2014 Cited by PubMed: 24957267 DOI: 10.1042/BJ20140614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation