4CHB
Crystal structure of the human KLHL2 Kelch domain in complex with a WNK4 peptide
Summary for 4CHB
Entry DOI | 10.2210/pdb4chb/pdb |
Related | 4CH9 |
Descriptor | KELCH-LIKE PROTEIN 2, SERINE/THREONINE-PROTEIN KINASE WNK4, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | signaling protein-transferase complex, klhl3, ubiquitin, adaptor protein, protein-binding, kelch repeat, wnk signalling pathway, signaling protein/transferase |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 69582.37 |
Authors | Sorrell, F.J.,Schumacher, F.R.,Kurz, T.,Alessi, D.R.,Newman, J.,Cooper, C.D.O.,Canning, P.,Kopec, J.,Williams, E.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A. (deposition date: 2013-11-29, release date: 2014-01-08, Last modification date: 2023-12-20) |
Primary citation | Schumacher, F.,Sorrell, F.J.,Alessi, D.R.,Bullock, A.N.,Kurz, T. Structural and Biochemical Characterisation of the Klhl3-Wnk Kinase Interaction Important in Blood Pressure Regulation. Biochem.J., 460:237-, 2014 Cited by PubMed: 24641320DOI: 10.1042/BJ20140153 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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