4CG5
Cryo-EM of the Sec61-complex bound to the 80S ribosome translating a secretory substrate
Summary for 4CG5
| Entry DOI | 10.2210/pdb4cg5/pdb |
| Related | 4CG6 4CG7 |
| EMDB information | 2511 |
| Descriptor | PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA (3 entities in total) |
| Functional Keywords | protein transport, ribosome, co-translational protein translocation |
| Biological source | CANIS LUPUS FAMILIARIS (DOG) More |
| Cellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein : P38377 Endoplasmic reticulum membrane; Single-pass membrane protein: P60058 P60467 |
| Total number of polymer chains | 3 |
| Total formula weight | 64024.49 |
| Authors | Gogala, M.,Becker, T.,Beatrix, B.,Barrio-Garcia, C.,Berninghausen, O.,Beckmann, R. (deposition date: 2013-11-21, release date: 2014-02-05, Last modification date: 2017-08-30) |
| Primary citation | Gogala, M.,Becker, T.,Beatrix, B.,Armache, J.,Barrio-Garcia, C.,Berninghausen, O.,Beckmann, R. Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion. Nature, 506:107-, 2014 Cited by PubMed: 24499919DOI: 10.1038/NATURE12950 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (7.4 Å) |
Structure validation
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