4CFH

Structure of an active form of mammalian AMPK

「2Y94」から置き換えられました

4CFH の概要

• エントリーDOI: 10.2210/pdb4cfh/pdb
• 関連するPDBエントリー: 4CFE 4CFF
• 分子名称: 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ... (6 entities in total)
• 機能のキーワード: transferase, transferase phosphorylation, active form, nucleotide-binding, staurosporine-binding, serine/threonine-protein kinase
• 由来する生物種: RATTUS NORVEGICUS (NORWAY RAT); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 108948.96

構造登録者

Xiao, B.,Sanders, M.J.,Underwood, E.,Heath, R.,Mayer, F.,Carmena, D.,Jing, C.,Walker, P.A.,Eccleston, J.F.,Haire, L.F.,Saiu, P.,Howell, S.A.,Aasland, R.,Martin, S.R.,Carling, D.,Gamblin, S.J. (登録日: 2013-11-18, 公開日: 2013-12-25, 最終更新日: 2023-12-20)

• 主引用文献: Xiao, B.,Sanders, M.J.,Underwood, E.,Heath, R.,Mayer, F.,Carmena, D.,Jing, C.,Walker, P.A.,Eccleston, J.F.,Haire, L.F.,Saiu, P.,Howell, S.A.,Aasland, R.,Martin, S.R.,Carling, D.,Gamblin, S.J.; Structure of Mammalian Ampk and its Regulation by Adp; Nature, 472:230-, 2011; PubMed: 21399626; DOI: 10.1038/NATURE09932

実験手法

X-RAY DIFFRACTION (3.24 Å)