4CE5

First crystal structure of an (R)-selective omega-transaminase from Aspergillus terreus

Summary for 4CE5

• Entry DOI: 10.2210/pdb4ce5/pdb
• Descriptor: AT-OMEGATA, PYRIDOXAL-5'-PHOSPHATE, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-GLUTAMIC ACID, ... (6 entities in total)
• Functional Keywords: transferase, aminotransferase, (r)-amine aminotransferase, enantioselectivity, chiral amines, transamination.
• Biological source: ASPERGILLUS TERREUS
• Total number of polymer chains: 2
• Total formula weight: 76204.62

Authors

Lyskowski, A.,Gruber, C.,Steinkellner, G.,Schurmann, M.,Schwab, H.,Gruber, K.,Steiner, K. (deposition date: 2013-11-08, release date: 2014-02-12)

• Primary citation: Lyskowski, A.,Gruber, C.,Steinkellner, G.,Schurmann, M.,Schwab, H.,Gruber, K.,Steiner, K.; Crystal Structure of an (R)-Selective Omega-Transaminase from Aspergillus Terreus; Plos One, 9:87350-, 2014; PubMed: 24498081; DOI: 10.1371/JOURNAL.PONE.0087350

Experimental method

X-RAY DIFFRACTION (1.63 Å)