4CCH

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with d5SICS as templating nucleotide

4CCH の概要

• エントリーDOI: 10.2210/pdb4cch/pdb
• 分子名称: DNA POLYMERASE I, THERMOSTABLE, 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOC)-3', 5'-D(*AP*AP*CP*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP* C)-3', ... (7 entities in total)
• 機能のキーワード: transferase-dna complex, unnatural nucleotide, artificial nucleotide, binary complex, klentaq, transferase/dna
• 由来する生物種: THERMUS AQUATICUS; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69819.15

構造登録者

Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. (登録日: 2013-10-23, 公開日: 2013-12-11, 最終更新日: 2024-05-08)

• 主引用文献: Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A.; Structural Insights Into DNA Replication without Hydrogen Bonds.; J.Am.Chem.Soc., 135:18637-, 2013; PubMed: 24283923; DOI: 10.1021/JA409609J

実験手法

X-RAY DIFFRACTION (2.55 Å)