4CB4
Structure of Influenza A H5N1 PB2 cap-binding domain with bound m7GTP
Summary for 4CB4
Entry DOI | 10.2210/pdb4cb4/pdb |
Related | 4CB5 |
Descriptor | POLYMERASE BASIC SUBUNIT 2, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | transferase, cap-binding inhibitors |
Biological source | INFLUENZA A VIRUS |
Total number of polymer chains | 1 |
Total formula weight | 19533.53 |
Authors | Pautus, S.,Sehr, P.,Lewis, J.,Fortune, A.,Wolkerstorfer, A.,Szolar, O.,Gulligay, D.,Lunardi, T.,Decout, J.L.,Cusack, S. (deposition date: 2013-10-10, release date: 2013-10-30, Last modification date: 2023-12-20) |
Primary citation | Pautus, S.,Sehr, P.,Lewis, J.,Fortune, A.,Wolkerstorfer, A.,Szolar, O.,Gulligay, D.,Lunardi, T.,Decout, J.L.,Cusack, S. New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain J.Med.Chem., 56:8915-, 2013 Cited by PubMed: 24134208DOI: 10.1021/JM401369Y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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