4C9V

Xenopus RNF43 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2

Summary for 4C9V

• Entry DOI: 10.2210/pdb4c9v/pdb
• Related: 4C84 4C85 4C86 4C8A 4C8C 4C8F 4C8P 4C8T 4C8U 4C8V 4C8W 4C99 4C9A 4C9E 4C9R 4C9V
• Descriptor: RNF43, R-SPONDIN-2 (2 entities in total)
• Functional Keywords: signaling protein, wnt, znrf3, rnf43, lgr4, lgr5, lgr6, rspo, r-spondin, r-spo, rspo1, rspo2, rspo3, rspo4, receptor, membrane, signalling
• Biological source: XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG); More
• Cellular location: Secreted (By similarity): Q5M7L6
• Total number of polymer chains: 2
• Total formula weight: 33765.19

Authors

Zebisch, M.,Jones, E.Y. (deposition date: 2013-10-03, release date: 2013-11-20, Last modification date: 2013-11-27)

• Primary citation: Zebisch, M.,Xu, Y.,Krastev, C.,Macdonald, B.T.,Chen, M.,Gilbert, R.J.C.,He, X.,Jones, E.Y.; Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.; Nat.Commun., 4:2787-, 2013; PubMed: 24225776; DOI: 10.1038/NCOMMS3787

Experimental method

X-RAY DIFFRACTION (2.7 Å)