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4C57

Structure of GAK kinase in complex with a nanobody

Summary for 4C57
Entry DOI10.2210/pdb4c57/pdb
Related4C58 4C59
DescriptorCyclin-G-associated kinase, NANOBODY, SULFATE ION, ... (6 entities in total)
Functional Keywordstransferase, kinase, conformational plasticity, activation
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total formula weight109002.92
Authors
Chaikuad, A.,Keates, T.,Krojer, T.,Allerston, C.K.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Muller-Knapp, S. (deposition date: 2013-09-10, release date: 2013-10-09, Last modification date: 2023-12-20)
Primary citationChaikuad, A.,Keates, T.,Vincke, C.,Kaufholz, M.,Zenn, M.,Zimmermann, B.,Gutierrez, C.,Zhang, R.,Hatzos-Skintges, C.,Joachimiak, A.,Muyldermans, S.,Herberg, F.W.,Knapp, S.,Muller, S.
Structure of Cyclin G-Associated Kinase (Gak) Trapped in Different Conformations Using Nanobodies.
Biochem.J., 459:59-, 2014
Cited by
PubMed: 24438162
DOI: 10.1042/BJ20131399
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

217705

數據於2024-03-27公開中

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