4C57
Structure of GAK kinase in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclin-G-associated kinase | polymer | 340 | 38183.6 | 2 | UniProt (O14976) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | C, D (C, D) | NANOBODY | polymer | 141 | 15670.3 | 2 | LAMA GLAMA (LLAMA) | ||
| 3 | E, K (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | F, G, H, I, L... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | J, M (A, B) | (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} | non-polymer | 365.4 | 2 | Chemie (FEF) | |||
| 6 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 14 - 351 (UniProt: O14976)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 107707.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1295.3 | |
| All* | Total formula weight | 109002.9 |
