4C3G

cryo-EM structure of activated and oligomeric restriction endonuclease SgrAI

4C3G の概要

• エントリーDOI: 10.2210/pdb4c3g/pdb
• EMDBエントリー: 2441
• 分子名称: SGRAIR RESTRICTION ENZYME, 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3' (3 entities in total)
• 機能のキーワード: hydrolase, restriction endonuclease, allostery, dna cleavage, parasite-host interaction
• 由来する生物種: STREPTOMYCES GRISEUS; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 100309.57

構造登録者

Lyumkis, D.,Talley, H.,Stewart, A.,Shah, S.,Park, C.K.,Tama, F.,Potter, C.S.,Carragher, B.,Horton, N.C. (登録日: 2013-08-23, 公開日: 2013-09-11, 最終更新日: 2017-08-23)

• 主引用文献: Lyumkis, D.,Talley, H.,Stewart, A.,Shah, S.,Park, C.K.,Tama, F.,Potter, C.S.,Carragher, B.,Horton, N.C.; Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.; Structure, 21:1848-, 2013; PubMed: 24055317; DOI: 10.1016/J.STR.2013.08.012

実験手法

ELECTRON MICROSCOPY (8.6 Å)