4C02
Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin
Summary for 4C02
Entry DOI | 10.2210/pdb4c02/pdb |
Descriptor | ACTIVIN RECEPTOR TYPE-1, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B, CITRATE ANION, ... (6 entities in total) |
Functional Keywords | transferase-isomerase complex, transferase, dorsomorphin, transferase/isomerase |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 51916.42 |
Authors | Williams, E.,Riesebos, E.,Vollmar, M.,Krojer, T.,Bradley, A.,Shrestha, L.,Kupinska, K.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A. (deposition date: 2013-07-31, release date: 2013-08-07, Last modification date: 2023-12-20) |
Primary citation | Williams, E.,Riesebos, E.,Vollmar, M.,Krojer, T.,Bradley, A.,Shrestha, L.,Kupinska, K.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A. Crystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin Ph D Thesis, |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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