4BZT

The Solution Structure of the MLN 944-d(ATGCAT)2 Complex

Summary for 4BZT

Related4BZU 4BZV
DescriptorDNA, 1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM (2 entities in total)
Functional Keywordsbis(phenazine-1-carboxamides), dna, intercalation, drug design, anticancer drug.
Biological sourceSYNTHETIC CONSTRUCT
Total number of polymer chains2
Total molecular weight4207.18
Authors
Serobian, A.,Thomas, D.S.,Ball, G.E.,Denny, W.A.,Wakelin, L.P.G. (deposition date: 2013-07-30, release date: 2013-08-21, Last modification date: 2014-09-03)
Primary citation
Serobian, A.,Thomas, D.S.,Ball, G.E.,Denny, W.A.,Wakelin, L.P.G.
The Solution Structure of Bis(Phenazine-1-Carboxamide)-DNA Complexes: Mln 944 Binding Corrected and Extended.
Biopolymers, 101:1099-, 2014
PubMed: 24898663 (PDB entries with the same primary citation)
DOI: 10.1002/BIP.22513
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

Clashscore4MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures