4BYH

Crystal structure of sialylated IgG Fc

4BYH の概要

• エントリーDOI: 10.2210/pdb4byh/pdb
• 分子名称: IG GAMMA-1 CHAIN C REGION, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: immune system, antibody, sialyation, immunoglobulin
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56486.86

構造登録者

Crispin, M.,Yu, X.,Bowden, T.A. (登録日: 2013-07-19, 公開日: 2013-08-21, 最終更新日: 2023-12-20)

• 主引用文献: Crispin, M.,Yu, X.,Bowden, T.A.; Crystal Structure of Sialylated Igg Fc: Implications for the Mechanism of Intravenous Immunoglobulin Therapy.; Proc.Natl.Acad.Sci.USA, 110:E3544-, 2013; PubMed: 23929778; DOI: 10.1073/PNAS.1310657110

実験手法

X-RAY DIFFRACTION (2.3 Å)