4BVN
Ultra-thermostable beta1-adrenoceptor with cyanopindolol bound
Summary for 4BVN
Entry DOI | 10.2210/pdb4bvn/pdb |
Descriptor | BETA-1 ADRENERGIC RECEPTOR, SODIUM ION, 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, ... (6 entities in total) |
Functional Keywords | signaling protein |
Biological source | MELEAGRIS GALLOPAVO (TURKEY) |
Total number of polymer chains | 1 |
Total formula weight | 38910.10 |
Authors | Miller, J.,Nehme, R.,Warne, T.,Edwards, P.C.,Leslie, A.G.W.,Schertler, G.,Tate, C.G. (deposition date: 2013-06-26, release date: 2014-04-02, Last modification date: 2023-12-20) |
Primary citation | Miller-Gallacher, J.L.,Nehme, R.,Warne, T.,Edwards, P.C.,Schertler, G.F.X.,Leslie, A.G.W.,Tate, C.G. The 2.1 A Resolution Structure of Cyanopindolol-Bound Beta1- Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor. Plos One, 9:92727-, 2014 Cited by PubMed: 24663151DOI: 10.1371/JOURNAL.PONE.0092727 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)