4BTS

THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A

これはPDB形式変換不可エントリーです。

4BTS の概要

• エントリーDOI: 10.2210/pdb4bts/pdb
• 分子名称: TRANSLATION INITIATION FACTOR EIF-1A FAMILY PROTEIN, 40S RIBOSOMAL PROTEIN RPS31E, 18S ribosomal RNA, ... (39 entities in total)
• 機能のキーワード: ribosome, translation, translation initiation, small ribosomal subunit, 40s, eif1a, eif1, translation initiation factor, eukaryotic translation initiation
• 由来する生物種: Tetrahymena thermophila SB210; 詳細
• 細胞内の位置: Cytoplasm : E6PBR9 E6PBR8
• タンパク質・核酸の鎖数: 144
• 化学式量合計: 4947943.00

構造登録者

Weisser, M.,Voigts-Hoffmann, F.,Rabl, J.,Leibundgut, M.,Ban, N. (登録日: 2013-06-19, 公開日: 2013-07-17, 最終更新日: 2023-12-20)

主引用文献

Weisser, M.,Voigts-Hoffmann, F.,Rabl, J.,Leibundgut, M.,Ban, N.
The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Nat. Struct. Mol. Biol., 20:1015-1017, 2013

PubMed Abstract: Eukaryotic translation initiation factors (eIFs) 1A and 1 are central players in the complex process of start-codon recognition. To improve mechanistic understanding of this process, we determined the crystal structure of the 40S ribosomal subunit in complex with eIF1A and eIF1 from Tetrahymena thermophila at a resolution of 3.7 Å. It reveals the positions of the two factors on the 40S and the conformational changes that accompany their binding.

PubMed: 23851459
DOI: 10.1038/nsmb.2622

実験手法

X-RAY DIFFRACTION (3.703 Å)