4BTL

Aromatic interactions in acetylcholinesterase-inhibitor complexes

Summary for 4BTL

Entry DOI	10.2210/pdb4btl/pdb
Descriptor	ACETYLCHOLINESTERASE, 4-(2-chloro-6-nitrophenoxy)-N-[2-(diethylamino)ethyl]benzenesulfonamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	acetylcholinesterase, hydrolase, inhibitor
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Total number of polymer chains	2
Total formula weight	129355.95
Authors	Andersson, C.D.,Forsgren, N.,Akfur, C.,Allgardsson, A.,Qian, W.,Engdahl, C.,Berg, L.,Ekstrom, F.,Linusson, A. (deposition date: 2013-06-18, release date: 2013-09-11, Last modification date: 2023-12-20)
Primary citation	Andersson, C.D.,Forsgren, N.,Akfur, C.,Allgardsson, A.,Berg, L.,Engdahl, C.,Qian, W.,Ekstrom, F.J.,Linusson, A. Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J.Med.Chem., 56:7615-, 2013 Cited by PubMed: 23984975 DOI: 10.1021/JM400990P PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation