4BSP

Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak

Summary for 4BSP

• Entry DOI: 10.2210/pdb4bsp/pdb
• Related: 4BSO
• Descriptor: R-SPONDIN-1, HOLMIUM ATOM, SULFATE ION, ... (4 entities in total)
• Functional Keywords: signaling protein, adult stem cell, leucine-rich repeat, g-protein coupled receptor, furin domain, wnt signaling, congenital anonychia
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted (By similarity): Q2MKA7
• Total number of polymer chains: 1
• Total formula weight: 14132.70

Authors

Peng, W.C.,de Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P. (deposition date: 2013-06-11, release date: 2013-06-19, Last modification date: 2013-07-24)

• Primary citation: Peng, W.C.,De Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P.; Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.; Cell Rep., 3:1885-, 2013; PubMed: 23809763; DOI: 10.1016/J.CELREP.2013.06.009

Experimental method

X-RAY DIFFRACTION (2 Å)