4BSO

Crystal structure of R-spondin 1 (Fu1Fu2) - Native

Summary for 4BSO

Entry DOI	10.2210/pdb4bso/pdb
Related	4BSP 4BSR 4BSS 4BST 4BSU
Descriptor	R-SPONDIN-1, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	signaling protein, adult stem cell, leucine-rich repeat g-protein coupled receptor, furin domain, wnt signaling, congenital anonychia
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted (By similarity): Q2MKA7
Total number of polymer chains	1
Total formula weight	14088.03
Authors	Peng, W.C.,de Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P. (deposition date: 2013-06-11, release date: 2013-06-19, Last modification date: 2013-07-24)
Primary citation	Peng, W.C.,De Lau, W.,Forneris, F.,Granneman, J.C.M.,Huch, M.,Clevers, H.,Gros, P. Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3:1885-, 2013 Cited by PubMed: 23809763 DOI: 10.1016/J.CELREP.2013.06.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation