4BQR
Mtb InhA complex with Methyl-thiazole compound 11
Summary for 4BQR
Entry DOI | 10.2210/pdb4bqr/pdb |
Related | 4BQP |
Descriptor | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (NZ)-2-[2,6-bis(fluoranyl)phenyl]-N-[5-[(1S)-1-(4-methyl-1,3-thiazol-2-yl)-1-oxidanyl-ethyl]-3H-1,3,4-thiadiazol-2-ylidene]ethanamide, ... (4 entities in total) |
Functional Keywords | oxidoreductase, methyl-thiazole |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 4 |
Total formula weight | 118458.56 |
Authors | Read, J.A.,Gingell, H.,Madhavapeddi, P.,Shirude, P.S. (deposition date: 2013-05-31, release date: 2013-12-11, Last modification date: 2024-05-08) |
Primary citation | Shirude, P.S.,Madhavapeddi, P.,Naik, M.,Murugan, K.,Shinde, V.,Nandishaiah, R.,Bhat, J.,Kumar, A.,Hameed, S.,Holdgate, G.,Davies, G.,Mcmiken, H.,Hegde, N.,Ambady, A.,Venkatraman, J.,Panda, M.,Bandodkar, B.,Sambandamurthy, V.K.,Read, J.A. Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting Inha in Mycobacterium Tuberculosis. J.Med.Chem., 56:8533-, 2013 Cited by PubMed: 24107081DOI: 10.1021/JM4012033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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