4BQA
Crystal structure of the ETS domain of human ETS2 in complex with DNA
Summary for 4BQA
Entry DOI | 10.2210/pdb4bqa/pdb |
Descriptor | PROTEIN C-ETS-2, 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP)-3', ... (4 entities in total) |
Functional Keywords | transcription, transcriptional regulator, dna complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: P15036 |
Total number of polymer chains | 9 |
Total formula weight | 67610.61 |
Authors | Newman, J.A.,Cooper, C.D.O.,Krojer, T.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Gileadi, O. (deposition date: 2013-05-30, release date: 2013-06-12, Last modification date: 2023-12-20) |
Primary citation | Newman, J.A.,Cooper, C.D.O.,Aitkenhead, H.,Gileadi, O. Structural Insights Into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2. J.Biol.Chem., 290:8539-, 2015 Cited by PubMed: 25670864DOI: 10.1074/JBC.M114.619270 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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