4BP1

Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Methylthioadenosine and Putrescine

4BP1 の概要

• エントリーDOI: 10.2210/pdb4bp1/pdb
• 関連するPDBエントリー: 4BP3
• 分子名称: SPERMIDINE SYNTHASE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 1,4-DIAMINOBUTANE, ... (6 entities in total)
• 機能のキーワード: transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold
• 由来する生物種: PLASMODIUM FALCIPARUM
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 98164.30

構造登録者

Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (登録日: 2013-05-23, 公開日: 2014-06-04, 最終更新日: 2023-12-20)

• 主引用文献: Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S.; Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design; Acta Crystallogr.,Sect.D, 71:484-, 2015; PubMed: 25760598; DOI: 10.1107/S1399004714027011

実験手法

X-RAY DIFFRACTION (2.17 Å)