4BIT

solution structure of cerebral dopamine neurotrophic factor (CDNF)

Summary for 4BIT

• Entry DOI: 10.2210/pdb4bit/pdb
• NMR Information: BMRB: 19164
• Descriptor: CEREBRAL DOPAMINE NEUROTROPHIC FACTOR (1 entity in total)
• Functional Keywords: signaling protein, parkinson
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted : Q49AH0
• Total number of polymer chains: 1
• Total formula weight: 18354.34

Authors

Latge, C.,Cabral, K.M.S.,Raymundo, D.P.,Foguel, D.,Herrmann, T.,Almeida, M.S. (deposition date: 2013-04-13, release date: 2014-04-23, Last modification date: 2023-06-14)

• Primary citation: Latge, C.,Cabral, K.M.S.,De Oliveira, G.A.P.,Raymundo, D.P.,Freitas, J.A.,Johanson, L.,Romao, L.F.,Palhano, F.L.,Herrmann, T.,Almeida, M.S.,Foguel, D.; The Solution Structure and Dynamics of Full-Length Human Cerebral Dopamine Neurotrophic Factor and its Neuroprotective Role Against Alpha-Synuclein Oligomers.; J.Biol.Chem., 290:20527-20540, 2015; PubMed: 26149686; DOI: 10.1074/JBC.M115.662254

Experimental method

SOLUTION NMR