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4BHF

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 4-(Trimethylammonio)pentanoate

Summary for 4BHF
Entry DOI10.2210/pdb4bhf/pdb
Related4BG1 4BGK 4BGM 4BHI 4C5W
DescriptorGAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, 4-(Trimethylammonio)pentanoic acid, ... (6 entities in total)
Functional Keywordsoxidoreductase, inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight45460.03
Authors
Tars, K.,Leitans, J.,Kazaks, A. (deposition date: 2013-04-02, release date: 2014-03-12, Last modification date: 2023-12-20)
Primary citationTars, K.,Leitans, J.,Kazaks, A.,Zelencova, D.,Liepinsh, E.,Kuka, J.,Makrecka, M.,Lola, D.,Andrianovs, V.,Gustina, D.,Grinberga, S.,Liepinsh, E.,Kalvinsh, I.,Dambrova, M.,Loza, E.,Pugovics, O.
Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase.
J.Med.Chem., 57:2213-, 2014
Cited by
PubMed: 24571165
DOI: 10.1021/JM401603E
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

217705

건을2024-03-27부터공개중

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