4BGK

Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with (3-(Trimethylammonio)propyl)phosphinate

Summary for 4BGK

Entry DOI	10.2210/pdb4bgk/pdb
Related	4BG1 4BGM 4BHF 4BHI 4C5W
Descriptor	GAMMA-BUTYROBETAINE DIOXYGENASE, N-OXALYLGLYCINE, trimethyl(3-oxidanylphosphonoylpropyl)azanium, ... (6 entities in total)
Functional Keywords	oxidoreductase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	45335.15
Authors	Tars, K.,Leitans, J.,Kazaks, A. (deposition date: 2013-03-27, release date: 2014-03-12, Last modification date: 2023-12-20)
Primary citation	Tars, K.,Leitans, J.,Kazaks, A.,Zelencova, D.,Liepinsh, E.,Kuka, J.,Makrecka, M.,Lola, D.,Andrianovs, V.,Gustina, D.,Grinberga, S.,Liepinsh, E.,Kalvinsh, I.,Dambrova, M.,Loza, E.,Pugovics, O. Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57:2213-, 2014 Cited by PubMed: 24571165 DOI: 10.1021/JM401603E PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation