4BBQ
Crystal structure of the CXXC and PHD domain of Human Lysine-specific Demethylase 2A (KDM2A)(FBXL11)
Summary for 4BBQ
Entry DOI | 10.2210/pdb4bbq/pdb |
Descriptor | LYSINE-SPECIFIC DEMETHYLASE 2A, 1,2-ETHANEDIOL, ZINC ION, ... (4 entities in total) |
Functional Keywords | oxidoreductase, ubiquitin, ligase, ubiquitination, demethylation, zf-cxxc dna binding domain, cpg island, chromatin, kdm2a, fbxl11 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus, nucleoplasm : Q9Y2K7 |
Total number of polymer chains | 2 |
Total formula weight | 27224.36 |
Authors | Allerston, C.K.,Watson, A.A.,Edlich, C.,Li, B.,Chen, Y.,Ball, L.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Laue, E.D.,Gileadi, O. (deposition date: 2012-09-27, release date: 2012-10-10, Last modification date: 2024-05-08) |
Primary citation | Allerston, C.K.,Watson, A.A.,Edlich, C.,Li, B.,Chen, Y.,Ball, L.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Laue, E.D.,Gileadi, O. Crystal Structure of the Cxxc and Phd Domain of Human Lysine-Specific Demethylase 2A (Kdm2A)(Fbxl11) To be Published, |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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