4BBQ

Crystal structure of the CXXC and PHD domain of Human Lysine-specific Demethylase 2A (KDM2A)(FBXL11)

4BBQ の概要

• エントリーDOI: 10.2210/pdb4bbq/pdb
• 分子名称: LYSINE-SPECIFIC DEMETHYLASE 2A, 1,2-ETHANEDIOL, ZINC ION, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, ubiquitin, ligase, ubiquitination, demethylation, zf-cxxc dna binding domain, cpg island, chromatin, kdm2a, fbxl11
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Nucleus, nucleoplasm : Q9Y2K7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27224.36

構造登録者

Allerston, C.K.,Watson, A.A.,Edlich, C.,Li, B.,Chen, Y.,Ball, L.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Laue, E.D.,Gileadi, O. (登録日: 2012-09-27, 公開日: 2012-10-10, 最終更新日: 2018-01-24)

• 主引用文献: Allerston, C.K.,Watson, A.A.,Edlich, C.,Li, B.,Chen, Y.,Ball, L.,Krojer, T.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,von Delft, F.,Laue, E.D.,Gileadi, O.; Crystal Structure of the Cxxc and Phd Domain of Human Lysine-Specific Demethylase 2A (Kdm2A)(Fbxl11); To be Published,

実験手法

X-RAY DIFFRACTION (2.24 Å)