4BB3

Isopenicillin N synthase with the dipeptide substrate analogue AhC

Summary for 4BB3

• Entry DOI: 10.2210/pdb4bb3/pdb
• Descriptor: ISOPENICILLIN N SYNTHASE, FE (III) ION, (2S)-2-azanyl-6-oxidanylidene-6-[[(2S)-1-oxidanyl-1-oxidanylidene-4-sulfanyl-butan-2-yl]amino]hexanoic acid, ... (5 entities in total)
• Functional Keywords: antibiotic biosynthesis, b-lactam antibiotic, oxidoreductase, oxygenase, penicillin biosynthesis
• Biological source: ASPERGILLUS NIDULANS FGSC A4
• Total number of polymer chains: 1
• Total formula weight: 37994.07

Authors

Daruzzaman, A.,Clifton, I.J.,Rutledge, P.J. (deposition date: 2012-09-19, release date: 2013-04-17, Last modification date: 2023-12-20)

• Primary citation: Daruzzaman, A.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J.; The Crystal Structure of Isopenicillin N Synthase with a Dipeptide Substrate Analogue.; Arch.Biochem.Biophys., 530:48-, 2013; PubMed: 23262315; DOI: 10.1016/J.ABB.2012.12.012

Experimental method

X-RAY DIFFRACTION (1.4 Å)