4BAO

Thrombin in complex with inhibitor

Summary for 4BAO

Related4BAH 4BAK 4BAM 4BAN 4BAQ
DescriptorTHROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN VARIANT-2, ... (7 entities in total)
Functional Keywordsserine protease, thrombin inhibitor, hydrolase
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted, extracellular space P00734 P00734
Secreted P09945
Total number of polymer chains3
Total molecular weight36157.08
Authors
Xue, Y.,Musil, D. (deposition date: 2012-09-14, release date: 2013-01-16, Last modification date: 2017-07-05)
Primary citation
Winquist, J.,Geschwindner, S.,Xue, Y.,Gustavsson, L.,Musil, D.,Deinum, J.,Danielson, U.H.
Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors.
Biochemistry, 52:613-, 2013
PubMed: 23290007 (PDB entries with the same primary citation)
DOI: 10.1021/BI301333Z
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.87 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.254304.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report