4BAD

Hen egg-white lysozyme structure in complex with the europium tris- hydroxymethyltriazoledipicolinate complex at 1.35 A resolution.

Summary for 4BAD

Entry DOI	10.2210/pdb4bad/pdb
Descriptor	LYSOZYME C, 4-(4-(hydroxymethyl)-1h-1,2,3-triazol-1-yl)pyridine-2,6-dicarboxylic acid, ACETATE ION, ... (7 entities in total)
Functional Keywords	hydrolase, click-chemistry, anomalous scattering, de novo phasing, experimental phasing, lanthanide complex, dipicolinate
Biological source	GALLUS GALLUS (CHICKENS, BANTAM)
Total number of polymer chains	1
Total formula weight	16009.61
Authors	Talon, R.,Kahn, R.,Gautier, A.,Nauton, L.,Girard, E. (deposition date: 2012-09-13, release date: 2012-11-14, Last modification date: 2024-10-23)
Primary citation	Talon, R.,Nauton, L.,Canet, J.,Kahn, R.,Girard, E.,Gautier, A. Clicked Europium Dipicolinate Complexes for Protein X-Ray Structure Determination. Chem.Commun.(Camb.), 48:11886-, 2012 Cited by PubMed Abstract: New trisdipicolinic acid-lanthanide complexes are reported as phasing agents for X-ray crystallography of proteins. It is demonstrated that CuAAC modifications allow protein co-crystallization with low concentration of lanthanide complexes leading to an accurate structure determination. PubMed: 23123834 DOI: 10.1039/C2CC36982F PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation