4B88

Ancestral (GNCA) Beta-lactamase class A

Summary for 4B88

Entry DOI	10.2210/pdb4b88/pdb
Related	3ZDJ
Descriptor	BETA-LACTAMASE, FORMIC ACID (3 entities in total)
Functional Keywords	hydrolase, antibiotic resistance
Biological source	SYNTHETIC CONSTRUCT
Total number of polymer chains	1
Total formula weight	28142.71
Authors	Gavira, J.A.,Risso, V.A.,Sanchez-Ruiz, J.M. (deposition date: 2012-08-24, release date: 2013-02-20, Last modification date: 2023-12-20)
Primary citation	Risso, V.A.,Gavira, J.A.,Mejia-Carmona, D.F.,Gaucher, E.A.,Sanchez-Ruiz, J.M. Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian Beta-Lactamases. J.Am.Chem.Soc., 135:2899-, 2013 Cited by PubMed: 23394108 DOI: 10.1021/JA311630A PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation