4B7Y
Crystal structure of the MSL1-MSL2 complex
Summary for 4B7Y
Entry DOI | 10.2210/pdb4b7y/pdb |
Descriptor | MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 2 HOMOLOG, ZINC ION (3 entities in total) |
Functional Keywords | gene regulation, dosage compensation, chromatin |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: Q68DK7 |
Total number of polymer chains | 4 |
Total formula weight | 36385.55 |
Authors | Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J. (deposition date: 2012-08-24, release date: 2013-02-06, Last modification date: 2023-12-20) |
Primary citation | Hallacli, E.,Lipp, M.,Georgiev, P.,Spielman, C.,Cusack, S.,Akhtar, A.,Kadlec, J. Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila. Mol.Cell, 48:587-, 2012 Cited by PubMed: 23084835DOI: 10.1016/J.MOLCEL.2012.09.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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