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4B4M

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Summary for 4B4M
Entry DOI10.2210/pdb4b4m/pdb
Related1FXO 1FZW 1G0R 1G1L 1G23 1G2V 1G3L 4B2X 4B3U 4B4B 4B4G 4B5B
DescriptorGLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, N-(6-amino-1-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-fluoro-N-methylbenzenesulfonamide, CHLORIDE ION, ... (5 entities in total)
Functional Keywordstransferase
Biological sourcePSEUDOMONAS AERUGINOSA
Total number of polymer chains4
Total formula weight137196.90
Authors
Alphey, M.S.,Pirrie, L.,Torrie, L.S.,Gardiner, M.,Westwood, N.J.,Gray, D.,Naismith, J.H. (deposition date: 2012-07-31, release date: 2012-10-31, Last modification date: 2023-12-20)
Primary citationAlphey, M.S.,Pirrie, L.,Torrie, L.S.,Boulkeroua, W.A.,Gardiner, M.,Sarkar, A.,Maringer, M.,Oehlmann, W.,Brenk, R.,Scherman, M.S.,McNeil, M.,Rejzek, M.,Field, R.A.,Singh, M.,Gray, D.,Westwood, N.J.,Naismith, J.H.
Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa.
ACS Chem. Biol., 8:387-396, 2013
Cited by
PubMed: 23138692
DOI: 10.1021/cb300426u
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

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