4B1B

Crystal structure of Plasmodium falciparum oxidised Thioredoxin Reductase at 2.9 angstrom

Summary for 4B1B

Entry DOI	10.2210/pdb4b1b/pdb
Descriptor	THIOREDOXIN REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	oxidoreductase, fad, nadph, thiol-mediated redox metabolism, class-i pyridine nucleotide-disulfide oxidoreductase, malaria
Biological source	PLASMODIUM FALCIPARUM
Cellular location	Cytoplasm (By similarity): Q25861
Total number of polymer chains	2
Total formula weight	121133.42
Authors	Boumis, G.,Giardina, G.,Dimastrogiovanni, D.,Angelucci, F.,Saccoccia, F.,Brunori, M.,Bellelli, A.,Miele, A.E. (deposition date: 2012-07-09, release date: 2012-08-29, Last modification date: 2023-12-20)
Primary citation	Boumis, G.,Giardina, G.,Angelucci, F.,Bellelli, A.,Brunori, M.,Dimastrogiovanni, D.,Saccoccia, F.,Miele, A.E. Crystal Structure of Plasmodium Falciparum Thioredoxin Reductase, a Validated Drug Target. Biochem.Biophys.Res.Commun., 425:806-, 2012 Cited by PubMed: 22889878 DOI: 10.1016/J.BBRC.2012.07.156 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation